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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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Drug ID
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DrugBank ID
KEGG ID
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ADR Ontology
ADR Term
Inflammation
ADR ID
BADD_A05823
ADR Hierarchy
08
General disorders and administration site conditions
08.01
General system disorders NEC
08.01.05
Inflammations
08.01.05.007
Inflammation
Description
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code
10061218
MeSH ID
D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Interleukin-1 alpha
P01583
T16340
Interleukin-10
P29456
Not Available
Interleukin-6
P05231
T32578
Interleukin-8
P10145
T22658
Nuclear receptor subfamily 4 group A member 3
Q92570
T93949
Retinol-binding protein 1
P09455
Not Available
Tumor necrosis factor
P01375
T20178
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00195
Azathioprine
0.006462%
BADD_D00203
Azithromycin
-
-
BADD_D00204
Azithromycin dihydrate
-
-
BADD_D00205
Azithromycin monohydrate
-
-
BADD_D00209
Baclofen
0.000673%
BADD_D00263
Betaxolol
-
-
BADD_D00274
Bimatoprost
-
-
BADD_D00284
Bortezomib
-
-
BADD_D00285
Bosentan
0.001788%
BADD_D00294
Brimonidine
0.001079%
BADD_D00303
Bromocresol green
-
-
BADD_D00318
Busulfan
-
-
BADD_D00330
Cabozantinib
0.001332%
BADD_D00344
Canagliflozin
-
-
BADD_D00347
Candesartan cilexetil
0.011564%
BADD_D00349
Capecitabine
0.002398%
BADD_D00356
Carbamazepine
0.003368%
BADD_D00364
Carboplatin
0.001598%
BADD_D00367
Carfilzomib
0.001066%
BADD_D00386
Cefepime
-
-
BADD_D00387
Cefepime hydrochloride
-
-
BADD_D00388
Cefixime
0.004974%
BADD_D00399
Ceftazidime
-
-
BADD_D00400
Ceftazidime pentahydrate
-
-
BADD_D00405
Ceftriaxone
0.061278%
BADD_D00410
Celecoxib
0.000804%
BADD_D00436
Chlorhexidine gluconate
-
-
BADD_D00471
Ciprofloxacin
-
-
BADD_D00474
Cisplatin
0.001598%
BADD_D00475
Citalopram
-
-
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